Glenn W. Knox, MD, JD, FACS, FACHE

Dr. Knox is a double board-certified ear surgeon and trained expert witness with over 40 years of experience treating and operating on ear, balance, and hearing conditions. He has expertise in all common otolaryngologic disorders with special interest in tinnitus, cholesteatoma, hearing loss, dizziness, and facial paralysis.

Currently, Dr. Knox is a Clinical Associate Professor in the Department of Pathology, Immunology, and Laboratory Medicine at the University of Florida, President of Nitinetics LLC, providing consulting and expert witness services and the Chief Medical Officer of Immunodominant, Inc., aiding in the development of antiviral therapies.

In addition to is medical expertise, Dr. Knox holds three United States patents and is the author of over sixty publications. Dr. Knox is active in medical research across his field with recent publications focusing on hearing disorders and balance function. Dr. Knox also holds a JD degree from Florida Coastal and is admitted to the Georgia Bar, giving him a unique understanding of the legal implications of the litigation process.

Services

Dr. Knox is experienced with the following issues:

• Acoustic neuroma
• Benign positional vertigo
• Cholesteatoma
• Dizziness
• Hearing protection devices
• Facial paralysis
• Head and neck surgery
• Hearing loss
• Implantable hearing devices
• Meniere's disease
• Middle ear prosthetics /implants
• Middle ear surgery
• Motion sickness
• Motor vehicle accidents – including airbag injuries
• Neurotology
• Otolaryngology
• Otologic effects of COVID-19
• Otologic medical devices intellectual property
• Otology
• Otosclerosis
• Skull base tumors
• Tinnitus
• (TBI) Traumatic brain injury associated with dizziness, hearing loss and/or tinnitus
• Traumatic facial injury
• Traumatic facial nerve paralysis
• Vestibular physiology

Areas of Expertise

Additional Expertise:

Balance, Cochlear Implant, Deafness, Imbalance, Facial Nerve, Head Trauma, Ear Injury, Airbag, Meniere's, Malpractice, Disability, TBI, Vertigo, Ear Ringing, Ear, COVID, IME, MVA, ENT, 3M, 3M EIF.

Professional Experience

University of Florida College of Medicine
Clinical Associate Professor — 2022–Present
Department of Pathology, Immunology, and Laboratory Medicine

Nitinetics, LLC — 2005-Present
Providing consulting, expert witness, and IME services. Specializing in dizziness, hearing loss, TBI, tinnitus, facial paralysis, and otologic medical devices IP.

Immunodominant, LLC — 2022-Present
Chief Medical Officer
Aiding in the development of antiviral therapies and research on protein expression, purification, and crystallization.

University of Florida Health Jacksonville
Associate Professor and Interim Chief, Division of Otolaryngology — 2019-2022
Director of Cochlear Implant Program and Surgical Staff, UF Health Skull Base Center — 2015-2022
Chief, Division of Otolaryngology — 2013–2015
Interim Chief, Division of Otolaryngology — 2012–2013
Associate Professor — 2010-2022
Courtesy Clinical Associate Professor — 1998–2010
Assistant Professor — 1991–1994

Mandarin Hearing and Balance Center — 1998-2013
Private Practice

University of Pennsylvania — 1994-1998
Director, University of Pennsylvania Balance Center and Assistant Professor

Licenses

Florida Medical License #ME75455 — Current

American Board of Otolaryngology Board Certified, Neurotology — 2012

American Board of Otolaryngology Board Certified — 1990

Legal Experience & Services

Sample Case Descriptions

Driver was rear-ended by another vehicle. After the MVA, driver noted hearing loss, tinnitus, and dizziness. The driver had hit his head but did not lose consciousness. Analysis included an estimate of trauma force involved. This was determined by 1) whether or not loss of consciousness occurred, 2) whether or not direct head impact occurred, 3) whether or not the airbag(s) deployed, and 4) whether or not seatbelts were worn. Audiograms, tests of balance function, as well as tinnitus handicap inventory were analyzed.

Hospital patient underwent an MRI. The loud noise allegedly caused hearing loss and tinnitus. Evaluation included analysis of audiograms, tinnitus handicap inventory, and whether or not ear protection was provided.

Patient underwent ear surgery. Postoperatively, patient allegedly suffered severe/profound hearing loss, tinnitus, and dizziness. Evaluation included examination of medical records, including audiograms and operative notes. Patient's deposition provided important information.

Construction worker fell from the roof of a building. Worker developed severe dizziness and imbalance. Analysis included evaluation of medical records, tests of balance function, and physical examinations.

Affiliations

American College of Healthcare Executives (Fellow)
American Neurotology Society (Fellow)
American Academy of Otolaryngology—Head and Neck Surgery
American College of Surgeons (Fellow)
Triological Society (Fellow)
Association for Research in Otolaryngology
Duval County Medical Society, Board of Directors, Member, 1998 to Present
Florida Medical Association
Greater Jacksonville ENT Society
Sigma Xi Scientific Honor Society
Society of NASA Flight Surgeons
Space Medicine Branch, Aerospace Medical Association
Aerospace Medical Association

Qualifications

American Board of Otolaryngology Board Certified, Neurotology — 2012
American Board of Otolaryngology Board Certified — 1990

Awards & Honors

Duval County Medical Society Delegate to the Florida Medical Association, 2004 - Present
John A. Beals Research Award-Review Category, Duval County Medical Society, 2014
40 Most Influential Healthcare Leaders in Jacksonville, 904 Magazine, 2014
Associate Fellow, Aerospace Medical Association, 2012
Law Review, Florida Coastal School of Law, 2007
Phi Delta Phi Legal Honor Society, 2007
Honor Award, American Academy of Otolaryngology—Head and Neck Surgery, 2005
Robert Wood Johnson Scholarship, 1980
Magna Cum Laude, Princeton University, 1977
Sigma Xi Scientific Honor Society, 1977

Seminars & Training

Presentations

"Otolaryngology Manifestations of COVID-19," University of Florida College of Medicine, Department of Pathology, Immunology and Laboratory Medicine Grand Rounds, Gainesville, Florida, December 29, 2021.

"Idiopathic Intracranial Hypertension: A Ground Based Analog for Visual Impairment Intercranial Pressure Syndrome?" Aerospace Medical Association Annual Meeting, Atlantic City, New Jersey, April 26, 2016.

"Temporal Bone Fractures and Facial Nerve Injury," U.F. Health—Jacksonville, Department of General Surgery Grand Rounds, September 2015.

"Genetic Factors in Motion Sickness," Aerospace Medical Association Annual Meeting, Orlando, Florida, May 13, 2015.

"Diabetes and Hearing Loss," Head to Toe Diabetes Care Conference, Jacksonville, Florida, November 15, 2014.

"Acoustic Neuroma," U.F. Health—Jacksonville, Department of Surgery Grand Rounds, September 4, 2013.

"Metallurgical Considerations in Shape-Memory Nitinol Middle Ear Prosthetics," American Academy of Otolaryngology—Head and Neck Surgery, Vancouver, BC, Canada, September 29–October 2, 2013.

"Complications Associated with Nitinol Prosthesis Use in Middle Ear Surgery," Combined Sections Meeting Triological Society, Scottsdale, Arizona, January 24, 2013.

"Motion Sickness Treatment Analysis with OVAR," American Academy of Otolaryngology—Head and Neck Surgery 2012 Annual Meeting, Washington, D.C., September 9, 2012.

"Proton Therapy for Acoustic Neuroma," Acoustic Neuroma Society—Jacksonville Chapter, Jacksonville, Florida, January 21, 2012.

"Understanding Legal Issues Impacting Physiatric Practice," American Academy of Physical Medicine and Rehabilitation, Orlando Florida, November 17, 2011.

"Implantable Hearing Devices," Hearing Loss Association of Jacksonville, Jacksonville, Florida, May 17, 2011.

"Off-Vertical Axis Rotational Assessment of Transdermal Scopolomine for Motion Sickness Prophylaxis," American Neurotology Society, Orlando, Florida, May 2, 2008.

"Pay for Performance: A Journey to the Dark Side," Combined Otolaryngologic Spring Meetings, Orlando, Florida, May 1, 2008.

"Shape-Memory Stapes Prosthesis for Otosclerosis Surgery," Triological Society Thesis Presentation, Boca Raton, Florida, 2005.

"Adaptation of Otolith Responses Assessed by Off-Vertical Axis Rotation," Banff, Alberta, Canada, 2003.

"Chronic Ear Disease and Cholesteatoma," Orange Park Medical Center, Orange Park, Florida, 2000.

"Torsional Nystagmus in Response to Centrifugal Acceleration," Eastern Section Meeting of the Triological Society, Boston, Massachusetts, 1998.

"Low Velocity Gunshot Wounds of the Temporal Bone," Eastern Sectional Meeting of the Triological Society, Philadelphia, Pennsylvania, 1996.

"Mixed Central and Peripheral Vestibular Pathology in Head Trauma," Combined Otolaryngologic Spring Meeting, Orlando, Florida, 1996.

Bigelow, D., Schmidt, M., and Knox, G. "Otolaryngologic Manifestations of Creutzfeldt-Jakob Syndrome" (abstract), American Academy of Otolaryngology—Head and Neck Surgery Annual Meeting, September 1995.

"Diagnosis and Management of Vertigo," Clinical Care Associates Continuing Medical Education (CME) update, Philadelphia, Pennsylvania, 1995.

"Motion Sickness Therapy," University of Pennsylvania Grand Rounds, Philadelphia, Pennsylvania, 1995.

"Vestibular Physiology, Audiology," Grand Rounds, Philadelphia, Pennsylvania, 1995.

"The Use of Anti-Convulsants for Motion Sickness and the Effect of Microgravity on Rat Skeletal Muscle," American Institute of Aeronautics and Astronautics Conference, Houston, Texas, 1995.

"Vestibular Physiology," University of Pennsylvania Grand Rounds, Philadelphia, Pennsylvania, 1995.

"Vestibular Physiology," University of Pennsylvania Basic Science Lecture, Philadelphia, Pennsylvania, 1995.

"Cerebellopontine Angle Neoplasms," Southern Illinois University (SIU) School of Medicine Department of Otorhinolaryngology Grand Rounds, Springfield, Illinois, 1994.

"Dizziness in Children," Children's Hospital of Philadelphia Neuroscience Conference, Philadelphia, Pennsylvania, 1994.

"Effect of Microgravity on Rat Masseter Muscle," Association for Research in Otolaryngology, St. Petersburg, Florida, 1994.

"Intracranial Complications of Otitis Media," University of Pennsylvania Grand Rounds Faculty Discussant, Philadelphia, Pennsylvania, 1994.

"Ménière's Syndrome," University of Pennsylvania Grand Rounds, Philadelphia, Pennsylvania, 1994.

"Motion Sickness Therapy," University of Pennsylvania Grand Rounds, Philadelphia, Pennsylvania, 1994

"Skeletal Muscle Changes in Microgravity," Annual Scientific Meeting, Aerospace Medicine Association, San Antonio, Texas, 1994.

"Surgery of Ménière's Syndrome," Baylor College of Medicine Grand Rounds, Houston, Texas, 1994.

"Surgical Management of Ménière's Syndrome," University of Pennsylvania Grand Rounds, Philadelphia, Pennsylvania, 1994.

Publications

Berkowitz, R.L., Bluhm, A.P., Knox, G.W., McCurdy, C.R., Ostrov, D.A. and Norris, M.H., 2023. Sigma Receptor Ligands Prevent COVID Mortality In Vivo: Implications for Future Therapeutics. International Journal of Molecular Sciences, 24(21), p.15718.

Ostrov, D.A. and Knox, G.W. (2022). Emerging mutation patterns in SARS-CoV-2 variants. Biochem Biophys Res Commun. 586:87-92.

Knox, G.W. (2016). Comment on "Long-term Outcomes After Middle Fossa Approach for Traumatic Facial Nerve Paralysis. Otology & Neurotology 2016. 37: 799-804." (Letter) Otology & Neurotology.

Knox, G.W. (2016). Idiopathic intracranial hypertension: a ground-based analog for visual impairment intracranial pressure syndrome? (abstract). Aerospace Medicine and Human Performance. 86 (3): P. 252.

Knox, G.W. (2015). Autologous bone grafts on demand during surgery with 3D CAD/CAM. (abstract). Otolaryngol HNS. 153 (1) P. 178.

Knox, G.W. (2015). Intraoperative autologous bone grafting with 3D CAD/CAM (abstract). Journal of Neurological Surgery B. 76: P. 62.

Knox, G.W. (2015). Carotid hemorrhage during skull base surgery: review of the literature, meta-analysis, and recommendations (abstract). Journal of Neurological Surgery B. 76: P. 40.

Knox, G.W. (2015). Genetic factors in motion sickness (abstract). Aerospace Medicine and Human Performance. 86 (3): P. 278.

Woodward, D., Knox, G.W., Wood, S., and DiBiase, C. (2014). Off-vertical axis rotational assessment of transdermal scopolamine for motion sickness prophylaxis. Gravitational and Space Research. 2 (2): PP. 13-20.

Knox, G.W. (2014). Motion sickness: an evolutionary and genetic basis for the negative reinforcement model. Aviation, Space and Environmental Medicine. 85 (1): PP. 46-49.

Knox, G.W. (2013). Metallurgical considerations in shape-memory nitinol middle ear prosthetics (abstract). Otolaryngology —Head and Neck Surgery Journal Supplement. 149 (2): P. 105.

Knox, G.W. (2013, March 6). Can you hear your body? Florida Times-Union, article.

Knox, G. W. (2013). In reference to late complications of nickel-titanium alloy stent in tracheal stenosis (letter). Laryngoscope. 123(2): P. 549. Article first published online: 30 Jan 2013. DOI: 10.1002/lary.23587.

Knox, G. W. (2013). Re: Rapid cVEMP and oVEMP responses elicited by a novel head striker and recording device (letter). Otology & Neurotology. 34 (4): P. 779.

Knox, G. W. (2012). Motion sickness treatment analysis with OVAR (abstract). Otolaryngology—Head and Neck Surgery. 147: P. 90.

Knox, G. W. Cochlear implantation in immunoglobulin M deficiency (abstract). Laryngoscope. Article first published online: 28 Jun 2011. DOI: 10.1002/lary.22072.

Knox, G. W. (2011). Re: Biocompatibility of nitinol stapes prosthesis by Roosli, Christof, Schmid, Philipp and Huber, Alex M. (letter). Otology & Neurotology. 32: P. 717.

Knox, G. W. (2010). CO2 laser-assisted posterior semicircular canal ablation for benign paroxysmal positional vertigo (abstract). Laryngoscope. 120: Supplement 4, 0.

Knox, G. W. (2006). Inhibition of influenza neuraminidase by elderberry lectin (abstract). Otolaryngology—Head and Neck Surgery. 135: P.123.

Knox, G. W., and Reitan, H. (2005, August). Shape-memory stapes prosthesis for otosclerosis surgery. Laryngoscope. 115(8): PP. 1340–1346.

Knox, G. W., and Woodard, D. (2004). Adaptation of otolith responses produced by off-vertical axis rotation (abstract). Otolaryngology—Head and Neck Surgery. 131: P. 263.

Suskind, D., and Knox, G. W. (2004). Dizziness in the Elderly. In M. A. Forciea, R. Lavizzo-Mourey, E.P. Schwab, and D. B. Raziano (Eds.), Geriatric Secrets. (PP. 74–79). Philadelphia, Pennsylvania: Hanley and Belfus.

Knox, G., and Reitan, H. (2003). The role of shape memory alloys in the treatment of otosclerosis (abstract). Trans. Otol. Rhin. Laryng. Soc.

Levine, M. E., Chillas, J. C., Stern, R. M., and Knox, G. W. (2000). The effects of serotonin (5-HT3) receptor antagonists on gastric tachyarrhythmia and the symptoms of motion sickness. Aviation Space and Environmental Medicine. 71(11 Pt 1): PP. 1111–1114.

Suskind, D. L., Bigelow, D. C., and Knox, G. (1999). Y modification of the Fisch meatoplasty. Otolaryngology-Head Neck Surgery. 121: PP. 126–127.

Keefe, M. A., Knox, G., McPherson, A., and Lopes, A. (1999). Atypical presentation of Waardenburg's syndrome type II. Otolaryngology-Head Neck Surgery. 120: P. 749.

Raney, R., Knox, G. W., and Jenkins, H. (1999). Hemangioma of the facial nerve. Otolaryngology-Head Neck Surgery. 120: PP. 946-947.

Bigelow, D. C., Kay, D. J., Rafter, K. O., Montes, M., Knox, G., and Yousem, D. M. (1998, March). Facial nerve stimulation from cochlear implants. American Journal of Otolaryngology. 19(2): PP. 163-169.

Knox, G. W. (1998). Treatment controversies in Bell palsy. Arch Otolaryngology-Head Neck Surgery. 124: PP. 821.

Altman, K. W., Austin, M. B., Tom L. W. C., and Knox, G. W. (1997). Complications of frontal sinusitis in adolescents: case presentations and treatment options. International Journal of Pediatric Otolaryngology. 41: PP. 19-20.

Knox, G. W. (1997). Granisetron as a treatment for dizziness after head trauma (abstract). Otolaryngology—Head and Neck Surgery. 117: P. 212.

Knox, G. W. (1996). Ménière's disease. American Family Physician.

Knox, G. (1996, September). AIDS and adenoidal hypertrophy (letter). Laryngoscope. 106(9): P. 1187.

Knox, G. (1996, May). Ondansetron for motion sickness. Aviation, Space, and Environmental Medicine. 67: P. 537.

Margardino, T. M., Deems, D.A. and Knox, G. W. Knox et al. (1996). Management of tracheoinnominate fistulas (abstract). Otolaryngology—Head and Neck Surgery. 115: P. 203.

Bigelow, D. C., Schmidt, D.E., and Knox, G. W. et al. (1995). Otolaryngologic manifestations of Creutzfeldt-Jakob syndrome—A case report (abstract). Otolaryngology—Head and Neck Surgery. 113: P. 202.

Knox, G. W., Woodard, D., Harris, R., and Dudley, G. (1995, May). Effect of microgravity on rat masseter muscle. AIAA Technical Publications.

Coker, N., and Knox, G. W. (1995). Temporal Bone Fractures. In Narayan, R. K., Wilberger, J. E, Jr., and Provlishock, J. T. (Eds.) Neurotrauma. New York City, New York: McGraw-Hill, Inc.

Knox, G. W., Woodard, D., et al. (1994, October). Phenytoin for motion sickness: clinical evaluation. Laryngoscope. 104(8 Pt. 1): PP. 935-939.

Knox, G. W., Woodard, D., Harris, R., and Dudley, G. (1994, May). Effect of microgravity on rat masseter muscle. Aviation, Space, and Environmental Medicine. 65: P. 432.

Knox, G. W. (1993, October). Otitis externa, Florida Times-Union, article.

Knox, G. W., and Watts, D. C. (1993, September). Juvenile active ossifying myxoma of the pediatric temporal bone (abstract). Otolaryngology—Head and Neck Surgery. 109: P. 230.

Knox, G. W., and Stiles, W. (1993, September). Facial nerve repair following gunshot wound of the temporal bone (abstract). Otolaryngology—Head and Neck Surgery. 109: P. 267.

Knox, G. W., Isaacs, J., Woodard, D., Johnson, L., and Jordan, D. (1993, March). Short latency vestibular evoked potentials. Otolaryngology—Head and Neck Surgery. 108(3): PP. 265–269.

Woodard, D., Knox, G., and Chelen, W. (1993). Phenytoin for motion sickness: operational use at Kennedy Space Center (abstract). Aviation, Space, and Environmental Medicine.

Knox, G. W. (1993). Lyme disease: otolaryngology manifestations. Baylor Head and Neck Newsletter-Winter.

Knox, G. W., Isaacs, J., and Woodard, D. (1992, September). Vestibular evoked potentials. Otolaryngology-Head Neck Surgery. 108: PP. 265-269.

Knox, G. W., Chiancone, G., and Ali, M. K. (1990, March). Squamous cell carcinoma arising in a plunging ranula. Journal of Oral and Maxillofacial Surgery. 48(3): PP. 305-308.

Ossoff, R., Duncavage, J., and Knox, G. W. (1990). Endoscopic Laser Arytenoidectomy. In R. K. Davis (Ed.), Lasers in Otolaryngology (PP. 44–48). Philadelphia: Saunders, Philadelphia.

Knox, G. W. (1990). Space motion sickness: an historical perspective (abstract). Aviation, Space, and Environmental Medicine. 61(132).

Jackson, C. G., Gulya, A., Knox, G. W., Glasscock, M. E., Pensak, M. L., Poe, D. S., and Johnson, G. D. (1989). A paraneoplastic syndrome associated with glomus tumors of the skull base? Preliminary observations. Otolaryngology—Head and Neck Surgery. 100(6): PP. 583–587.

Glasscock, M., Jackson, C. G., and Knox, G. W. (1988, November). Can acquired immunodeficiency syndrome and Creutzfeldt-Jakob disease be transmitted via otologic homografts? Archives of Otolaryngology-Head Neck Surgery. 114(11): PP. 1252–1255.

Knox, G. W., and Frable, M. A. S. (1987). Adventures in smoking: add oxygen (letter). Journal of the American Medical Association. 258(10): P. 1333.

Knox, G. W., and Frable, M. A. S. (1987). Conservative management of nasal mucosal burns (abstract). Transactions of the American Laryngological, Rhinological, and Otological Society.

Knox, G. W., and Frable, M. A. S. (1986). Smoking and oxygen, a lethal mix. Virginia Medical Quarterly. 113(8): P. 431.

Chan, V., Clayton, R. N., Knox, G. W., and Catt, K. J. (1981). Ontogeny of pituitary GnRH receptors. Endocrinology. 108(6)PP. 2086–2092.

Crerar, D. L., Means, J. L., Yuretich, R. F., Amster, M. P., Hastings, D. W., Knox, G. W., Lyon, K. E., and Quiett, R. F. (1981). Hydrogeochemistry of the New Jersey coastal plain. Chemical Geology. 33(1-4): PP. 23–44.

Kaney, A. R., and Knox, G. W. (1980, August). Production of melanin in precursors by a mutant of tetrahymena thermophila. Journal of Protozoology. 27(3): PP. 339–341.

Harwood, J. P., Clayton, R. N., Chen, T. T., Knox, G. W., and Catt, K. J. (1980). Ovarian gonadotropin-releasing hormone receptors: regulation and effects on ovarian development. Endocrinology. 107(2): PP. 414–421.

Education

Juris Doctor; Law Review editorial staff; Phi Delta Phi — 2008
Florida Coastal School of Law, Jacksonville, Florida

Medical Doctor — 1983
Rutgers Medical School, Piscataway, New Jersey

Master of Arts in Biochemistry — 1979
Bryn Mawr College, Bryn Mawr, Pennsylvania

Bachelor of Arts, magna cum laude, Geology and Geophysics — 1977
Princeton University, Princeton, New Jersey

Post Doctoral Training

Fellowship — Neurotology — 1993–1994
Baylor College of Medicine, Houston, Texas

Residency — Otolaryngology — 1987–1989
Vanderbilt University Medical Center. Nashville, Tennessee

Residency — Otolaryngology — 1984–1986
Medical College of Virginia, Richmond, Virginia

Internship — General Surgery — 1983–1984
Indiana University Hospitals, Indianapolis, Indiana

Continuing Education

Flight Surgeon Training, Johnson Space Center, 1993.
Endoscopic Sinus Surgery, University of Pennsylvania, 1992.
Mode 6 Shuttle Rescue Exercise, Kennedy Space Center (KSC), 1992.
Skull Base Workshop, Ear Research Foundation, 1992.
Midas Rex Skull Base Surgery Course, Ear Research Foundation, 1992.
KSC Shuttle Emergency Medical Support Course, Kennedy Space Center, 1991.
Endoscopic Sinus Surgery, University of Florida, 1991.
Endoscopic Sinus Surgery, Vanderbilt University, 1989.
Laser Surgery Course, Vanderbilt University, 1989.
Basic ENT Science Course, University of Iowa, 1985.